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KMID : 0892920170260010066
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Experimental Neurobiology
2017 Volume.26 No. 1 p.66 ~ p.69
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Relapsing Polychondritis Presented with Encephalitis Followed by Brain Atrophy
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Ahn Suk-Won
Park Moo-Seok
Jeong Hae-Bong
Kwon Oh-Sang
Yoon Byung-Nam
Kim Hee-Sung
Choi Sang-Tae
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Abstract
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Relapsing polychondritis (RP) is a rare autoimmune disease that is characterized by inflammatory reaction of unknown etiology and destruction of cartilaginous structures. Characteristic symptoms of this disease include cartilage inflammation of the ear, nose, larynx, trachea, bronchi, joints, eyes, heart and skin. Concomitance with neurologic symptom is very rare in RP, and the detailed underlying mechanism of neurological involvement associated with RP is not fully understood. We herein described an unusual recurrent case of inflammatory brain lesions associated with RP, with attention to clinical manifestations, autoimmune disease involvement, and therapeutic effects.
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KEYWORD
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Relapsing polychondritis, Encephalitis, Brain atrophy, Multiple sclerosis, Neuromyelitis optica
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